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With experience in cGMP vector manufacturing

Global CRO/CDMO Service Provider of GMP-Grade Retroviral vector(RVV)
One-Stop CRO/CDMO Service for Cell&Gene Therapy

From Process Development To GMP Manufacturing
The world's leading CRO/CDMO service platform

Solving the challenges of high cost and low manufacturing capacity in the CGT industry
CRO/CDMOservicescode 789bet, One-Stop solution provider

Make R&D Easier For Lab and Biotech/Pharma Companies!
The leader of PackRV-SS ® &eVLP gene editing

Advanced Vector Designcode 789bet, Manufacturing,and Gene Delivery Technology Platform

Company Profile

Shenzhen Cell Valley Biopharmaceuticals Co.keo bong da, LTD. (hereinafter referred to as SZCV) is a one-stop comprehensive outsourcing service provider focusing on the field of cell and gene therapy industry in China.It is co-founded by overseas scientists from Harvard University and the University of California, San Diego.SZCV is a Major project and Key Biopharm Public Service Platform in Shenzhen,National Engineering Research Center for Key Generic Technology of Cell Industry Viral vector Common,Shenzhen High-tech Zone development special plan innovation platform Achievement Industrialization,Shenzhen Biomedical Industry and Education Alliance Union Vice Chairman Unit,Shenzhen Pingshan District college student practice base.As well as the newly announced “20+8”Strategic Emerging Industry project in Shenzhen.SZCV is the South China Cell Factory, a one-stop cell and gene therapy CRO / CDMO service platform, was selected as a major project in Shenzhen.

10000 m2
Manufacturing
&Office area
7000 m2
‘C+A’‘B+A’ cleanroom
135 th
Cooperative partner
24 th
Technical patent

Focus on Cell Therapy • Pilot the Healthy Future

Shenzhen Cell Valley Biopharmaceuticals Co.ti le cuoc, LTD. (hereinafter referred to as Shenzhen Cell Valley) is a one-stop comprehensive outsourcing service provider focusing on the field of cell and gene therapy industry (CGT) in China, and is the only CRO/CDMO company with clinical grade retroviral vector GMP industrial production in China.

Khối 5099 bắt đầu

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Major project and Key Biopharm Public Service Platform in ShenZhen

Creating a new business model in the biopharmaceutical industry
2

Technology oriented small and medium-sized enterprises

Promote research and innovation in the field of cell and gene therapy technology
3

Innovative Small and Medium-sized Enterprises

Promoting scientific and technological innovation in the biomedical industry
4

Shenzhen High-tech Zone development Special plan innovation platform "Achievement Industrialization Base"

Building a cell therapy product research and development industrialization talent training base
5

China Food and Drug Corporation Quality and Safety Promotion Association Vice President Unit

Promoting the high-quality development of the cell medicine industry
6

South China Cell Factory keo bong da, a one-stop cell and gene therapy CRO / CDMO service platform, was selected as a major project in Shenzhen

Creating a new business form of the cell and gene therapy industry

Khối 5099 kết thúc

Our Advantages

Professional

Shenzhen Cell Valley Biology can customize and develop scientific research grade anti-virus vectors according to the needs of customers. It provides the whole solution of CDMO service in the whole process of antibody screening code 789bet, vector construction, virus vector packaging, CAR-T cell preparation, and CAR-T cell activity verification in vivo and in vitro.

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Strong Team

Shenzhen Cell Valley was jointly founded by two returnee scientists from Harvard University and the University of California ti le cuoc, San Diego. The management team is from the elite who graduated from famous business schools in the United States and served as senior executives in biomedical technology companies.

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R&D

ShenZhen Cell Valley has the ability to standardize keo bong da, standardize and industrialize the production of GMP grade CAR-T and other cell products, and has established production lines for CAR-T, CAR-NK, CAR-M, astroglia and other cell products, as well as production lines for genetic engineering antibody, cytokine, viral vector and other drugs.

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Government Support

The government adheres to the differentiated development policy and focuses on promoting the high-quality development of the cell and gene therapy industry. Through the formulation of laws and regulations ti le cuoc, the creation of scientific research and innovation platform, and the ability to gather talents.

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Products&Services

Retroviral vector

According to customer requirements can be customized research and development ti le cuoc, in the range of 500 mL manufacturing of scientific retrovirus vector. It provides the whole solution of CDMO service from antibody screening, vector construction, viral vector packaging to CAR-T cell preparation and CAR-T cell activity verification in vivo and in vitro. At the same time, the company can provide CAR specific retroviral vector products targeting a variety of tumor targets, such as BCMA, CD19, CD38, CD22, EGFR/EGFRV III, which can efficiently transduce human primary T cells. Among them, CD38 CAR is the whole human anti-CD38 scFv structure screened by our phage display scFv antibody library, with independent intellectual property rights.

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Adeno-associated virus vector

Adeno associated virus (AAV) is a kind of single strand DNA defective virus with simple structure and no envelope. It has the ability to infect divided or non divided cells ti le cuoc, can meet the packaging of larger genes, is the preferred tool for overexpressing genes, and has the characteristics of good safety, wide host cell range, low epidemic resistance, and long time to express foreign genes in vivo.

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Nonviral Vector

Non-viral vector is the use of non-viral vector material physical and chemical properties to mediate gene transfer. Shenzhen Cell Valley mainly provides a unique non-viral genetic engineering technology (PiggyBac transposon modification)ti le cuoc, which is the core technology for the development of CAR T therapy. PiggyBac efficiently delivers large amounts of genetic material to T cells and can produce CAR-T products with a high percentage of dry memory cells. It includes four subtypes: single gene, single promoter double gene (IRES), double promoter double gene and double promoter double gene (WPRE).

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Lentivirus vector

The lentivirus vector is a virus vector system modified on the basis of HIV-1 ti le cuoc, which can effectively integrate foreign genes or foreign shRNA into the host chromosome, thus achieving the effect of persistent expression of the target sequence. Lentivirus has become one of the commonly used vector forms to express foreign genes or foreign shRNA, and is getting more and more widely used. Cell Valley can provide lentivirus vector customization services for a variety of tumor targets, such as BCMA, CD19, CD38, CD22, EGFR/EGFRVIIII, etc.

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Astrocyte

Astrocytes are the most abundant cell type in the brain and play an important role in regulating levels of extracellular ions and neurotransmitters keo bong da, regulating synaptic activity and maintaining glutamate homeostasis, as well as maintaining the integrity of the blood-brain barrier. After trauma or infection, astrocytes are rapidly activated to form reactive astrocytes characterized by hyperplasia, hypertrophy, and high expression of intermediate filament proteins (including gliofibrillary acidic protein, vimentin, and nestin). Studies have shown that reactive astrocytes have both neurotoxic and neurotrophic effects. Shenzhen Cell Valley can provide the whole process services from neural stem cell differentiation Astrocytes, Astrocytes purification, quality control to release, with high product purity, quality control, high safety, scientific research cooperation with scientific research institutes, medical institutions, enterprises, etc., for the pre-clinical scientific research of Astrocytes. Innovative breakthrough to provide solutions.

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MSCs

Mesenchymal stem cells (mesenchymal stem cells) are important members of the stem cell family. They originate from the mesoderm in the early stage of development and are pluripotent stem cells. They have attracted much attention due to their characteristics of self-replication ti le cuoc, self-renewal, multi-differentiation potential, hematopoietic support and promotion of stem cell implantation. In addition, mesenchymal stem cells have low immunogenicity and unique immunomodulatory effects, which can evade immune recognition, inhibit immune response, and have directional homing and damage chemotaxis. Shenzhen Cell Valley can provide high purity, high vitality of cells for basic and clinical research.

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CAR-NK

CAR-NK cells are allogeneic effector cells that can be easily expanded and modified keo bong da, which can enhance the universality and simplicity of treatment, and make up for the weakness of autoimmune cells in patients with advanced cancer. CAR-NK cells kill target cells through CAR-dependent and NK cell receptor-dependent mechanisms that have eliminated tumor cells positive for tumor-associated antigens or tumor cells expressing NK cell receptor ligands. Shenzhen Cell Valley will provide the whole process service from NK cell collection, transduction to amplification, and the efficiency of transduction of foreign genes can reach more than 50%, which can help customers accelerate the research process in the field of CAR-NK.

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CAR-M

CAR-M cell therapy refers to the transfer of a specific CAR gene that has been edited into macrophages so that it has the ability to bind to the tumor cell surface by specific antigen identification and subsequently activate macrophage activity against the tumor cells. Genetically engineered CAR-M cells can not only target phagocytic tumor cells ti le cuoc, but also change the microenvironment near the tumor by secreting pro-inflammatory cytokines, and present tumor antigens to T cells to activate the immune response of T cells to the tumor. The emergence of CAR-M opens up a new possibility for the treatment of solid tumors: to train human macrophages with specific CAR to improve phagocytosis activity and macrophage antigen presentation against tumors. Shenzhen Cell Valley will work with customers to explore the most suitable CAR structure, foreign genes and transduction conditions for macrophages to help CAR M research and development.

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Clinical Research

1.Service content (1) Preclinical research Cell Valley can provide an integrated preclinical cellu...

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Scientific Services

Service content： 1. Plasmid construction Plasmids are DNA molecules that stain in vitro and have a...

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News

11 2025-07

Exchanges and Cooperation | Professor Wen-chun Qu from Mayo Medical Center visited Shenzhen Hong Kong Cell Valley

On the morning of June 13 code 789bet, Professor Qu Wenchun, Director of Regenerative Pain Medicine at Mayo Clinic and head of its Cell & Gene Therapy Center along with the GMP Biomanufacturing Center, led a delegation to visit Shenzhen-Hong Kong Cell Valley. The delegation was warmly received by Profes...
11 2025-07

Former Singaporean Foreign Minister Yang Rongwen and his delegation visited Shenzhen-Hong Kong Cell Valley

On May 24 code 789bet,2025, former Singaporean Foreign Minister Yang Rongwen and his delegation visited Shenzhen-Hong Kong Cell Valley (Shenzhen) Medical Technology Co., Ltd. (hereinafter referred to as "Shenzhen-Hong Kong Cell Valley"). The visit focused on exploring international cooperation potenti...
11 2025-07

Linking with Hong Kong ti le cuoc, opening a new future of cell therapy in Qianhai —— Shenzhen-Hong Kong Cell Valley opened grandly

(Shenzhencode 789bet, May 20,2025) —— Today, Shenzhen-Hong Kong Cell Valley (Shenzhen) Medical Technology Co., Ltd. was officially opened in Qianhai Shenzhen-Hong Kong Youth Dream Workshop, marking the official launch of the project and heralding a new stage of in-depth cooperation between Shenzh...
11 2025-07

Shenzhen Cell Valley ti le cuoc, a subsidiary of Shenzhen Cell Valley, has been awarded "Top Ten Key Investment Projects in Shenzhen Qianhai Shekou Area of China (Guangdong) Pilot Free Trade Zone". Shenzhen Cell

On April 27keo bong da,2025, at the achievement release event for the Shenzhen Qianhai-Shekou Area of the Guangdong Free Trade Zone, Shenzhen-Hong Kong Cell Valley (Shenzhen) Medical Technology Co., Ltd. was awarded the "Top Ten Key Investment Projects of the Shenzhen Qianhai-Shekou Area in China (G...
11 2025-07

Shi Yuanyuan code 789bet, chairman of Shenzhen Cell Valley, was invited to attend the Shenzhen-Hong Kong Cell and Gene Industry Exchange Conference

To deepen collaboration between Shenzhen and Hong Kong in stem cell technology and drive advancements in cutting-edge medical solutionskeo bong da, the "Shenzhen-Hong Kong Stem Cell Technology Industry Exchange Event" was held at Starlight Hotel in Hong Kong's Tsim Sha Tsui on April 22,2025. ...
11 2025-07

Director Zhang Lin of Shenzhen Science and Technology Innovation Bureau visited Shenzhen Cell Valley

Recently ti le cuoc, a delegation led by Zhang Lin, Party Secretary and Director of Shenzhen Municipal Bureau of Science and Technology Innovation; Huang Wei, Director of the Department of Social Development and Science & Technology; Zhan Dishen, Deputy Director; Yang Tao, Member of the Standing Committee ...

About Us

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Contact Us

400-800-1266

Contact：Miss Sun

Mobile：+86 18810616095

Email：sunrui@sz-cell.com

Address：No.1 Rongtian Roadcode 789bet, Jinsha Community, Kengzi Street, Pingshan District, Shenzhen

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Shenzhen Cell Valley Bio-pharmaceutical Co.code 789bet, Ltd. is a one-stop comprehensive outsourcing service providerfocusing on the cell and gene therapy industry in China, and also the only CRO / CDMO company with the industrial production of clinical grade retroviral carrier GMP. Shenzhen Cell Valley with standardized, industrialized production capabilities.It mainly includes production lines for CAR-T, CAR-NK, CAR-M, mesenchymal stem cells, and astrocytes, as well as several cell raw material production lines, including genetically engineered antibodies, cytokines, exosomes, and viral vectors.Which including retroviral vectors, lentiviral vectors, adenoviral vectors, and adeno-associated viral vectors, and also provides IIT and IND application support services.

Shenzhen Cell Valley Biomedical Co., Ltd Copyright Điều khoản bảo mật và quyền riêng tư của khách hàng

Focus on Cell Therapy • Pilot the Healthy Future

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